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New PublicationsASTHMA THERAPEUTICS MCP-1566
A GLOBAL STRATEGIC BUSINESS REPORT
CONTENTS
I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS
Study Reliability And Reporting Limitations I-1
Disclaimers I-2
Data Interpretation & Reporting Level I-2
Quantitative Techniques & Analytics I-3
Product Definitions And Scope Of Study I-3
Inhaled Corticosteroids: I-3
Beta-2 Adrenoreceptor Agonists I-4
Combinations I-4
Anti- leukotrienes I-4
Others I-4
Antihistamines I-4
Methylxanthines I-4
Mast Cell Stabilizers I-5
Monoclonal Antibodies I-5
Anticholinergics I-5
II. EXECUTIVE SUMMARY
1. Market Overview II-1
Current & Future Analysis II-1
Competitive Outlook II-1
Major Asthma Therapeutics by Class II-2
Facts about Asthma II-2
2. Trends & Issues II-3
Combination Drugs - Rule the World II-3
Novel Compounds To Pep Up Growth II-3
Rise in Pediatric Asthma To Keep Market Lucrative II-3
Toxic Nature of Asthma Drugs - A Serious Concern II-3
Life Threatening Drugs Under Regulatory Scan II-3
3. Product Overview II-4
Causes of Asthma II-4
Allergens II-4
Irritants II-4
Other Factors II-4
Classes in Asthma II-5
A. Mild Intermittent Asthma: II-5
B. Mild Persistent Asthma: II-5
C. Moderate Persistent Asthma: II-5
D. Severe Persistent Asthma: II-5
Asthma Treatments II-6
Combination Asthma Medications II-6
Over-the-Counter Asthma Medications II-6
Immunotherapy (Allergy shots) II-6
Alternative Therapies II-6
Asthma Therapeutics II-6
Corticosteroids II-7
Beta-2 Adrenoreceptor Agonists II-7
Mast Cell Stabilizers II-7
Monoclonal Antibodies II-7
Immune System: Natural Defenders II-7
Human Antibodies II-8
Polyclonal and Monoclonal Antibodies II-8
Leukotriene Inhibitors II-8
Methylxanthines: II-8
Combination Therapeutics: II-8
Off Label Therapeutics: II-8
Anticholinergics: II-8
Antihistamines: II-9
Asthma Therapeutics by Various Classes II-9
4. Product Launches/Innovations II-10
Future to Witness A Novel Therapeutic in Asthma Treatment II-10
Dr. Reddy's Releases Doxobid in India II-10
Novartis Files Approval for Xolair to Enter Japanese Market II-10
AstraZeneca Receives Approval for Symbicort II-10
GSK Alters Labels for Two Asthma Drugs II-10
DMI BioSciences Starts Evaluating DMI 8393 II-11
Inflazyme Begins Phase IIb Trial for IPL512,602 II-11
Neurim Develops A Neuroprotective Compound II-11
Xolair Forays into UK II-11
Critical Therapeutics Rolls Out ZYFLO II-11
Ivax Corp. Introduces Qvar EasiBreathe Inhaler II-12
Altana Rolls Out Respiratory Drug, Alvesco in the UK II-12
Sepracor Launches XOPENEX HFA II-12
Polyphor Commences Research for Protease Inhibitors II-12
Novartis Plans to Apply for A New Drug Approval II-12
Asmanex Twisthaler 220 mcg Receives US FDA Approval II-12
GroPep Completes Pre-Clinical Testing of T-Cell Peptide Drug II-13
Able Laboratories Obtains FDA Approval II-13
Acceleration Therapeutics' AT-101 Passes Laboratory Test II-13
Pharmaxis' New Tool to Assess Asthma Passes Clinical Trial II-13
Aventis Seeks FDA Approval Alvesco II-13
Schering-Plough Releases Asmanex Twisthaler II-13
FDA Clears Xolair to Enter US Market II-14
Sepracor Completes Phase III Trial for XOPENEX II-14
Pfizer Conducts Phase II Clinical Studies II-14
Celera and Bayer Plans to End Collaboration II-14
Banyu and Kyorin Starts Distribution of Asthma Treatment II-14
GlaxoSmithKline Introduces Advair II-14
Novartis Gets FDA Approval for Foradil Aerolizer II-14
5. Recent Industry Activity II-15
Teva Purchases Ivax II-15
SkyePharma Strikes A Deal with KOSP II-15
Ranbaxy Inks an In-Licensing Agreement with Eurodrug II-15
Pfizer and Rigel Forms A Collaboration II-15
MAP and Elan Extends Agreement II-15
Glenmark Collaborates with Teijin Pharma II-16
Pfizer Acquires Meridica II-16
Bayer and Apax Forms A New Company II-16
KOSP Signs Multiple Agreements II-16
Novartis Pharma Inks A Licensing Agreement with Ivax II-17
LAB Intends to Purchase Seyvika II-17
ALTANA and Tanabe Signs A Pact II-17
6. Focus on Select Players II-18
Abbott Laboratories (US) II-18
ALTANA Pharma AG (Germany) II-18
AstraZeneca (UK) II-18
Boehringer Ingelheim (Germany) II-19
Genentech, Inc. (US) II-19
GlaxoSmithKline (UK) II-19
Merck & Co., Inc. (US) II-19
Novartis Pharma AG (Switzerland) II-19
Pfizer Inc. (US) II-20
Schering-Plough Corporation (US) II-20
Sepracor Inc. (US) II-20
The Sanofi-Aventis Group (US) II-21
3M (US) II-21
7. Global Market Perspective II-22
Table 1: World Recent Past, Current and Future Analysis for
Asthma Therapeutics by Geographic Region - US, Canada, Japan,
Europe and Rest of World Markets Independently Analyzed by
Annual Sales for the Years 2000 through 2010 in US$ Million
(includes corresponding Graph/Chart) II-22
Table 2: World 10-Year Perspective for Asthma Therapeutics by
Geographic Region - Percentage Breakdown of Dollar Sales for
US, Canada, Japan, Europe and Rest of World Markets for the
Years 2000, 2006 and 2010 (includes corresponding Graph/Chart) II-22
Table 3: World Recent Past, Current and Future Analysis for
Inhaled Corticosteroids by Geographic Region - US, Canada,
Japan, Europe and Rest of World Markets Independently Analyzed
by Annual Sales for the Years 2000 through 2010 in US$
Million (includes corresponding Graph/Chart) II-23
Table 4: World 10-Year Perspective for Inhaled Corticosteroids
by Geographic Region - Percentage Breakdown of Dollar Sales
for US, Canada, Japan, Europe and Rest of World Markets for
the Years 2000, 2006 and 2010 (includes corresponding
Graph/Chart) II-23
Table 5: World Recent Past, Current and Future Analysis for
Short Acting Beta Agonists by Geographic Region - US, Canada,
Japan, Europe and Rest of World Markets Independently Analyzed
by Annual Sales for the Years 2000 through 2010 in US$ Million
(includes corresponding Graph/Chart) II-24
Table 6: World 10-Year Perspective for Short Acting Beta
Agonists by Geographic Region - Percentage Breakdown of Dollar
Sales for US, Canada, Japan, Europe and Rest of World Markets
for the Years 2000, 2006 and 2010 (includes corresponding
Graph/Chart) II-24
Table 7: World Recent Past, Current and Future Analysis for
Long Acting Beta Agonists by Geographic Region - US, Canada,
Japan, Europe and Rest of World Markets Independently Analyzed
by Annual Sales for the Years 2000 through 2010 in US$
Million (includes corresponding Graph/Chart) II-25
Table 8: World 10-Year Perspective for Long Acting Beta
Agonists by Geographic Region - Percentage Breakdown of
Dollar Sales for US, Canada, Japan, Europe and Rest of World
Markets for the Years 2000, 2006 and 2010 (includes
corresponding Graph/Chart) II-25
Table 9: World Recent Past, Current and Future Analysis for
Combinations by Geographic Region - US, Canada, Japan, Europe
and Rest of World Markets Independently Analyzed by Annual
Sales for the Years 2000 through 2010 in US$ Million
(includes corresponding Graph/Chart) II-26
Table 10: World 10-Year Perspective for Combinations by
Geographic Region - Percentage Breakdown of Dollar Sales for
US, Canada, Japan, Europe and Rest of World Markets for the
Years 2000, 2006 and 2010 (includes corresponding Graph/Chart) II-26
Table 11: World Recent Past, Current and Future Analysis for
Anti-Leukotrienes by Geographic Region - US, Canada, Japan,
Europe and Rest of World Markets Independently Analyzed by
Annual Sales for the Years 2000 through 2010 in US$ Million
(includes corresponding Graph/Chart) II-27
Table 12: World 10-Year Perspective for Anti-Leukotrienes by
Geographic Region - Percentage Breakdown of Dollar Sales for
US, Canada, Japan, Europe and Rest of World Markets for the
Years 2000, 2006 and 2010 (includes corresponding
Graph/Chart) II-27
Table 13: World Recent Past, Current and Future Analysis for
Other Asthma Therapeutics by Geographic Region - US, Canada,
Japan, Europe and Rest of World Markets Independently Analyzed
by Annual Sales for the Years 2000 through 2010 in US$ Million
(includes corresponding Graph/Chart) II-28
Table 14: World 10-Year Perspective for Other Asthma
Therapeutics by Geographic Region - Percentage Breakdown of
Dollar Sales for US, Canada, Japan, Europe and Rest of World
Markets for the Years 2000, 2006 and 2010 (includes
corresponding Graph/Chart) II-28
III. MARKET
1. The United States III-1
A.Market Analysis III-1
Current & Future Analysis III-1
Asthma Reflections in the US III-1
Competitive Scenario III-1
Table 15: Leading Anticholinergic Companies in the US
(2006): Percentage Breakdown of Market Share for
Boehringer Ingelheim, Dey Inc, Alpharma and Others
(includes corresponding Graph/Chart) III-1
Product Launches/Innovations III-2
Strategic Developments III-4
Focus on Key Players III-5
3M III-5
Abbott Laboratories III-5
Genentech, Inc. III-5
Merck & Co., Inc. III-6
Pfizer Inc. III-6
Schering-Plough Corporation III-6
Sepracor Inc. III-6
The Sanofi-Aventis Group III-7
B.Market Analytics III-8
Table 16: US Recent Past, Current and Future Analysis for
Asthma Therapeutics by Product Segment - Inhaled
corticosteroids, Short acting beta agonists, Long acting
beta agonists, Combinations, Anti- leukotrienes and Other
Asthma Therapeutics Markets Independently Analyzed by Annual
Sales for the Years 2000 through 2010 in US$ Million
(includes corresponding Graph/Chart) III-8
Table 17: US 10-Year Perspective for Asthma Therapeutics by
Product Segment - Percentage Breakdown of Dollar Sales for
Inhaled corticosteroids, Short acting beta agonists, Long
acting beta agonists, Combinations, Anti- leukotrienes and
Other Asthma Therapeutics Markets for the Years 2000, 2006
and 2010 (includes corresponding Graph/Chart) III-9
2. Canada III-10
A.Market Analysis III-10
Current & Future Analysis III-10
Product Launches/Innovations III-10
Strategic Development III-10
B.Market Analytics III-11
Table 18: Canadian Recent Past, Current and Future Analysis
for Asthma Therapeutics by Product Segment - Inhaled
corticosteroids, Short acting beta agonists, Long acting
beta agonists, Combinations, Anti- leukotrienes and Other
Asthma Therapeutics Markets Independently Analyzed by Annual
Sales for the Years 2000 through 2010 in US$ Million
(includes corresponding Graph/Chart) III-11
Table 19: Canadian 10-Year Perspective for Asthma
Therapeutics by Product Segment - Percentage Breakdown of
Dollar Sales for Inhaled corticosteroids, Short acting beta
agonists, Long acting beta agonists, Combinations, Anti-
leukotrienes and Other Asthma Therapeutics Markets for the
Years 2000, 2006 and 2010 (includes corresponding
Graph/Chart) III-12
3. Japan III-13
A.Market Analysis III-13
Current & Future Analysis III-13
Product Approvals/Launches III-13
Strategic Developments III-13
B.Market Analytics III-14
Table 20: Japanese Recent Past, Current and Future Analysis
for Asthma Therapeutics by Product Segment - Inhaled
corticosteroids, Short acting beta agonists, Long acting
beta agonists, Combinations, Anti- leukotrienes and Other
Asthma Therapeutics Markets IndependentlyAnalyzed by Annual
Sales for the Years 2000 through 2010 in US$ Million
(includes corresponding Graph/Chart) III-14
Table 21: Japanese 10-Year Perspective for Asthma
Therapeutics by Product Segment - Percentage Breakdown of
Dollar Sales for Inhaled corticosteroids, Short acting beta
agonists, Long acting beta agonists, Combinations, Anti-
leukotrienes and Other Asthma Therapeutics Markets for the
Years 2000, 2006 and 2010 (includes corresponding
Graph/Chart) III-15
4. Europe III-16
Market Analysis III-16
Current & Future Analysis III-16
Table 22: European Recent Past, Current and Future Analysis
for Asthma Therapeutics by Geographic Region - France,
Germany, UK, Italy, Spain and Rest of Europe Independently
Analyzed by Annual Sales for the Years 2000 through 2010 in
US$ Million (includes corresponding Graph/Chart) III-16
Table 23: European Recent Past, Current and Future Analysis
for Asthma Therapeutics by Product Segment - Inhaled
corticosteroids, Short acting beta agonists, Long acting
beta agonists, Combinations, Anti- leukotrienes and Other
Asthma Therapeutics Markets Independently Analyzed by Annual
Sales for the Years 2000 through 2010 in US$ Million
(includes corresponding Graph/Chart) III-17
Table 24: European 10-Year Perspective for Asthma
Therapeutics by Geographic Region - Percentage Breakdown of
Dollar Sales for France, Germany, UK, Italy, Spain and Rest
of Europe for the Years 2000, 2006 and 2010 (includes
corresponding Graph/Chart) III-18
Table 25: European 10-Year Perspective for Asthma
Therapeutics by Product Segment - Percentage Breakdown of
Dollar Sales for Inhaled corticosteroids, Short acting beta
agonists, Long acting beta agonists, Combinations, Anti-
leukotrienes and Other Asthma Therapeutics Markets for the
Years 2000, 2006 and 2010 (includes corresponding
Graph/Chart) III-19
4a. France III-20
Market Analysis III-20
Current & Future Analysis III-20
Table 26: French Recent Past, Current and Future Analysis
for Asthma Therapeutics by Product Segment - Inhaled
corticosteroids, Short acting beta agonists, Long acting
beta agonists, Combinations, Anti- leukotrienes and Other
Asthma Therapeutics Markets Independently Analyzed by Annual
Sales for the Years 2000 through 2010 in US$ Million
(includes corresponding Graph/Chart) III-20
Table 27: French 10-Year Perspective for Asthma Therapeutics
by Product Segment - Percentage Breakdown of Dollar Sales
for Inhaled corticosteroids, Short acting beta agonists,
Long acting beta agonists, Combinations, Anti- leukotrienes
and Other Asthma Therapeutics Markets for the Years 2000,
2006 and 2010 (includes corresponding Graph/Chart) III-21
4b. Germany III-22
A.Market Analysis III-22
Current & Future Analysis III-22
Product Launches/Innovations III-22
Focus on Key Players III-22
ALTANA Pharma AG III-22
Boehringer Ingelheim III-22
B.Market Analytics III-23
Table 28: German Recent Past, Current and Future Analysis
for Asthma Therapeutics by Product Segment - Inhaled
corticosteroids, Short acting beta agonists, Long acting
beta agonists, Combinations, Anti- leukotrienes and Other
Asthma Therapeutics Markets Independently Analyzed by Annual
Sales for the Years 2000 through 2010 in US$ Million
(includes corresponding Graph/Chart) III-23
Table 29: German 10-Year Perspective for Asthma Therapeutics
by Product Segment - Percentage Breakdown of Dollar Sales
for Inhaled corticosteroids, Short acting beta agonists,
Long acting beta agonists, Combinations, Anti- leukotrienes
and Other Asthma Therapeutics Markets for the Years 2000,
2006 and 2010 (includes corresponding Graph/Chart) III-24
4c. The United Kingdom III-25
A.Market Analysis III-25
Current & Future Analysis III-25
Product Launches/Innovations III-25
Strategic Developments III-26
Focus on Key Players III-26
AstraZeneca III-26
GlaxoSmithKline III-26
B.Market Analytics III-27
Table 30: UK Recent Past, Current and Future Analysis for
Asthma Therapeutics by Product Segment - Inhaled
corticosteroids, Short acting beta agonists, Long acting
beta agonists, Combinations, Anti- leukotrienes and Other
Asthma Therapeutics Markets Independently Analyzed by Annual
Sales for the Years 2000 through 2010 in US$ Million
(includes corresponding Graph/Chart) III-27
Table 31: UK 10-Year Perspective for Asthma Therapeutics by
Product Segment - Percentage Breakdown of Dollar Sales for
Inhaled corticosteroids, Short acting beta agonists, Long
acting beta agonists, Combinations, Anti- leukotrienes and
Other Asthma Therapeutics Markets for the Years 2000, 2006
and 2010 (includes corresponding Graph/Chart) III-28
4d. Italy III-29
Market Analysis III-29
Current & Future Analysis III-29
Table 32: Italian Recent Past, Current and Future Analysis
for Asthma Therapeutics by Product Segment - Inhaled
corticosteroids, Short acting beta agonists, Long acting
beta agonists, Combinations, Anti- leukotrienes and Other
Asthma Therapeutics Markets Independently Analyzed by Annual
Sales for the Years 2000 through 2010 in US$ Million
(includes corresponding Graph/Chart) III-29
Table 33: Italian 10-Year Perspective for Asthma
Therapeutics by Product Segment - Percentage Breakdown of
Dollar Sales for Inhaled corticosteroids, Short acting beta
agonists, Long acting beta agonists, Combinations, Anti-
leukotrienes and Other Asthma Therapeutics Markets for the
Years 2000, 2006 and 2010 (includes corresponding
Graph/Chart) III-30
4e. Spain III-31
Market Analysis III-31
Current & Future Analysis III-31
Table 34: Spanish Recent Past, Current and Future Analysis
for Asthma Therapeutics by Product Segment - Inhaled
corticosteroids, Short acting beta agonists, Long acting
beta agonists, Combinations, Anti- leukotrienes and Other
Asthma Therapeutics Markets Independently Analyzed by Annual
Sales for the Years 2000 through 2010 in US$ Million
(includes corresponding Graph/Chart) III-31
Table 35: Spanish 10-Year Perspective for Asthma
Therapeutics by Product Segment - Percentage Breakdown of
Dollar Sales for Inhaled corticosteroids, Short acting beta
agonists, Long acting beta agonists, Combinations, Anti-
leukotrienes and Other Asthma Therapeutics Markets for the
Years 2000, 2006 and 2010 (includes corresponding
Graph/Chart) III-32
4f. Rest of Europe III-33
A.Market Analysis III-33
Current & Future Analysis III-33
Product Approvals/Launches III-33
Strategic Development III-34
Focus on Select Player III-34
Novartis Pharma AG (Switzerland) III-34
B.Market Analytics III-35
Table 36: Rest of Europe Recent Past, Current and Future
Analysis for Asthma Therapeutics by Product Segment -
Inhaled corticosteroids, Short acting beta agonists, Long
acting beta agonists, Combinations, Anti- leukotrienes and
Other Asthma Therapeutics Markets Independently Analyzed by
Annual Sales for the Years 2000 through 2010 in US$ Million
(includes corresponding Graph/Chart) III-35
Table 37: Rest of Europe 10-Year Perspective for Asthma
Therapeutics by Product Segment - Percentage Breakdown of
Dollar Sales for Inhaled corticosteroids, Short acting beta
agonists, Long acting beta agonists, Combinations, Anti-
leukotrienes and Other Asthma Therapeutics Markets for the
Years 2000, 2006 and 2010 (includes corresponding
Graph/Chart) III-36
5. Rest of World III-37
A.Market Analysis III-37
Current & Future Analysis III-37
Product Launches III-37
Strategic Developments III-37
B.Market Analytics III-38
Table 38: Rest of World Recent Past, Current and Future
Analysis for Asthma Therapeutics by Product Segment -
Inhaled corticosteroids, Short acting beta agonists, Long
acting beta agonists, Combinations, Anti- leukotrienes and
Other Asthma Therapeutics Markets Independently Analyzed by
Annual Sales for the Years 2000 through 2010 in US$ Million
(includes corresponding Graph/Chart) III-38
Table 39: Rest of World 10-Year Perspective for Asthma
Therapeutics by Product Segment - Percentage Breakdown of
Dollar Sales for Inhaled corticosteroids, Short acting beta
agonists, Long acting beta agonists, Combinations, Anti-
leukotrienes and Other Asthma Therapeutics Markets for the
Years 2000, 2006 and 2010 (includes corresponding
Graph/Chart) III-39
IV. COMPETITIVE LANDSCAPE
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