Significant dimensions of the vast parallel studies afforded by biochips have created a holistic means of viewing biological systems. In addition to the combination of various sciences, space, time and expense are all key factors in the future development of biochips. Modern day chips can contain a human genome comprising of 30,000 to 100,000 genes.

The biochip industry is in the early stages of growth and hence, not only promises potential but also is susceptible to vagaries of market forces. Competition, patent disputes, knowledge constraints (in terms of skilled employees, technical know-how) and financial strength might be a few impediments for firms engaged in this industry. A promising market arises from three factors – an aging population, third party reimbursement and a growing number of individuals suffering from common chronic diseases. Biochips would certainly evolve in terms of physical, technical characteristics, and with focus on miniaturization of assays, they would turn smaller and more powerful with each generation. The industry is characterized by both intense rivalry and equally well-developed web of alliances.
 

TABLE OF CONTENTS 

BIOCHIPS			BMR-1001


                                        CONTENTS



  1. METHODOLOGY                                                           1
      Study Reliability and Reporting Limitations                          1
      Disclaimers                                                          2
      Quantitative Techniques & Reporting Level                            3

  2. INDUSTRY OVERVIEW                                                     4
      Promising Biochips Promote Biological  Research                      4
      Market Scenario across Products  and Regions                         4
       DNA Chips Lead the Application Front                                5
      Probable Industry Directions                                         5
       Biochip Technology Boosts Personalised Medicine                     6
       Biochip Technology Spreads beyond  Pharma Industry                  7
       Protein Chips to Shape the Future                                   7
       Proteomics “Chip” into Biochip Technology                           8
       Towards Increasing Minaturization                                   8
       European Advancements Set Diagnostic  Procedures                    8
      Competitive Scenario                                                 8
       Major Participants                                                  8
       Roche and Affymetrix Taste Success  in the Diagnostics Market       10
      Growing Partnerships between Pharma  and Biotech Companies           10
      Tech Giants Join the Biochip Fray                                    11

  3. PRODUCT FACTS                                                         12
      A. DNA Chips                                                         12
      B. Protein Chips                                                     13
      C. Lab Chips                                                         13

  4. APPLICATIONS OF BIOCHIPS                                              13
      Biochip Uses                                                         14
       Biochips and Pharmaceutical  Investigation                          14
       Biochips and Medical Diagnostics                                    15
        Advantages of Biosensor Chip  Technology                           15
       Biochips and Forensics                                              16
       Biochips and Transplantation Screening                              16
       Biochips and Identity Testing                                       16
       Biochips and Water and Environmental  Testing                       16
      Food Industry                                                        16

  5. TRENDS                                                                17
      Industry Characteristics                                             17
       New Products and Players to  Drive Market                           17
      Key Forces Boosting the Industry                                     17
      Industry Structure                                                   17
      Industry Challenges                                                  18
       Price Dearness Pauses Biochips  Growth                              18
      Current Approaches to Biochips                                       19
      The Business of Biochips                                             19
      Technological Trends                                                 20
       Sensitivity                                                         20
       Microfabrication                                                    20
       Density                                                             20
       Integrated Chips                                                    21
       Patent Trends                                                       21
        Patent Applications                                                21

  6. NEXT GENERATION TECHNOLOGY                                            22
      Microfluidics Using CD-ROM Technology                                22

  7. CORPORATE DEVELOPMENTS                                                23
      Affymetrix Acquires USB                                              23
      Illumina Announces Partnership with Genpathway for ChIP
       Sequencing Services                                                 23
      Affymetrix and Avesthagen Enter into an  Agreement                   24
      Roche NimbleGen and Affymetrix Announce  Expansion of License
       Agreement                                                           24
      GATC Biotech Establishes New Subsidiary                              25
      Affymetrix Introduces Complete  Cytogenetic Solution                 25
      Sigma Launches ChIP Kit                                              25
      US and Czech Scientists to Develop  Biochips for Detecting Cancer    26
      Roche Takes Over NimbleGen                                           26
      GenTel BioSciences Acquires Protein  Chip Platform Assets of GSK     27
      Advanced Liquid Logic Acquires Nanolytics                            27
      Applied Microarrays Acquires Select  GE Healthcare’s Assets          27
      Affymetrix and Partners Healthcare  Extend Collaboration             28
      Agencourt, NuGEN and Affymetrix  Clinical Services Collaborate       29
      Affymetrix Inks Licensing Agreement  with Empire Genomics            29
      Caliper Enters into a Licensing Agreement  with Monogram
       Biosciences                                                         30
      Affymetrix and IPSOGEN Sign Agreement                                30
      bioMérieux and NuGEN Enter into Supply  and Cross-License
       Agreement                                                           31
      VWR and CapitalBio Enter into  a Distribution Agreement              31
      UCL Subsidiary and Roche Diagnostics  Ink Licensing Deal             32
      Affymetrix Establishes the European Cytogenetic Research
       Initiative.                                                         32
      Roche Introduces Gene Expression  Services and Arrays                32
      Affymetrix Unveils Affymetrix GeneChip Command Console Software      33
      Affymetrix Introduces GeneChip Mouse  and Rat Gene 1.0 ST Arrays     33
      Affymetrix Unveils Genome-Wide Human  SNP Array 6.0                  34
      Caliper Life Sciences Launches High Throughput RNA Assay             35
      Applied Biosystems Unveils DNA Tools                                 35
      febit Launches Geniom RT Analyzer                                    35
      Austrian Research Center Develops  New Biochip Surface               36
      Researchers Develop Biochips to Eliminate Animal Testing             36

  8. MAJOR PLAYERS                                                         37
      Affymetrix (US)                                                      37
      Applied Biosystems Group (US)                                        37
      Biomerieux (France)                                                  37
      Bio-Rad Laboratories, Inc. (US)                                      37
      Caliper Life Sciences, Inc. (US)                                     37
      Cepheid Inc. (US)                                                    38
      GE Healthcare Ltd (UK)                                               38
      Takara Bio, Inc. (Japan)                                             38
      Zyomyx (US)                                                          38

  9. MARKET ANALYTICS                                                      39

  10. THE UNITED STATES                                                    43
      Biochips Market Overview                                             43
      Time Saving Biochips  - All Set to Grow                              43
      Multiple Applications of Biochips Drive Sales                        43
      Biochip Market Faces Challenges                                      43

  11. CANADA                                                               45

  12. JAPAN                                                                46
      DNA Chip Based on Printing Technology                                46
      DNA Chips to Reveal Links Among Genes                                47
      A Leading Japanese Biochip Player -  Takara Shuzo                    47
      ICAN ™ Technology for Large-Scale  Production of DNA Fragments       48

  13.  EUROPE                                                              50

  a. France                                                                52

  b. Germany                                                               53

  c. The United Kingdom                                                    55

  d. Rest of Europe                                                        56

  14. REST OF WORLD                                                        57
       China                                                               58
       Basic Environment and Commercial  Development                       58
       Biochip Research                                                    58
       Status of Biochip Industry in China                                 59
      Taiwan                                                               59
       Taiwan Pursues Promise of Biochip Sector                            59
       International Advantage Sought                                      60


 EXHIBITS

      Table 1: Market Shares of Biochips Patent Applications in the
      World - 2003

      Table 2: Global Biochips Market by Region for the Period
      2007-2015 (Sales in US$ Million)

      Table 3: Percentage Breakdown of Global Biochips Market by
      Region for the Years 2008 & 2012

      Table 4: Global DNA Chips Market by Region for the Period
      2007-2015 (Sales in US$ Million)

      Table 5: Percentage Breakdown of Global DNA Chips Market by
      Region for  the Years 2008 & 2012

      Table 6: Global Protein Chips Market by Region for the Period
      2007-2015 (Sales in US$ Million)

      Table 7: Percentage Breakdown of Global Protein Chips Market
      by Region for the Years 2008 & 2012

      Table 8: Global Lab Chips Market by Region for the Period
      2007-2015 (Sales in US$ Million)

      Table 9: Percentage Breakdown of Global Lab Chips Market by
      Region for the Years 2008 & 2012

      Table 10: Biochips Market by Segment  in the US: 2007-2015
      (Sales in  US$ Million)

      Table 11: Percentage Breakdown of  Biochips Market by Segment
      in the US  for the Years 2008 & 2012

      Table 12: Biochips Market by Segment  in Canada: 2007-2015
      (Sales in US$ Million)

      Table 13: Percentage Breakdown of Biochips Market by Segment
      in Canada for the Years 2008 & 2012

      Table 14: Biochips Market by Segment  in Japan: 2007-2015
      (Sales in  US$ Million)

      Table 15: Percentage Breakdown of Biochips Market by Segment
      in Japan for the Years 2008 & 2012

      Table 16: Biochips Market by Region in Europe: 2007-2015
      (Sales in US$ Million)

      Table 17: Percentage Breakdown of Biochips Market by Region in
      Europe  for the Years 2008 & 2012

      Table 18: Biochips Market by Segment in Europe: 2007-2015
      (Sales in US$ Million)

      Table 19: Percentage Breakdown of  Biochips Market by Segment
      in Europe for the Years 2008 & 2012

      Table 20: Biochips Market by Segment in France: 2007-2015
      (Sales in US$ Million)

      Table 21: Percentage Breakdown of Biochips Market by Segment
      in France for the Years 2008 & 2012

      Table 22: Biochips Market by Segment in Germany: 2007-2015
      (Sales in US$ Million)

      Table 23: Percentage Breakdown of Biochips Market by Segment
      in Germany  for the Years 2008 & 2012

      Table 24: Biochips Market by Segment in the UK: 2007-2015
      (Sales in US$ Million)

      Table 25: Percentage Breakdown of  Biochips Market by Segment
      in the UK  for the Years 2008 & 2012

      Table 26: Biochips Market by Segment in Rest of Europe:
      2007-2015 (Sales in US$ Million)

      Table 27: Percentage Breakdown of Biochips Market by Segment
      in Rest of Europe for the Years 2008 & 2012

      Table 28: Biochips Market by Segment in Rest of World:
      2007-2015 (Sales in US$ Million)

      Table 29: Percentage Breakdown of Biochips Market by Segment
      in Rest of World  for the Years 2008 & 2012


 COMPANIES PROFILED

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