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Nanotechnology in Medical Applications: The Global Market

Price:
CAD $5,165.25
ISBN/SKU #:
GB-HLC069A
Research Group:
BCC
Date of Publication:
January 2010
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Summary

The aim of this report is to provide detailed market, technology and industry analyses to help readers quantify and qualify the market for prescription drug products incorporating nanotechnology features. Important trends are identified and sales forecasts by product categories and major country markets are provided through 2014; these are based on industry sources and considered assessment of the regulatory environment, healthcare policies, demographics, and other factors that directly affect the nanomedicine-related drug market. The wider economic environment is also taken into account.

The report examines strategies employed by companies specializing in nanomedicine to meet the challenges of this highly competitive market.
 
Nanomedicine is transforming itself into an established market. Unlike some of the farther shores of nanotechnology, which are still largely experimental in nature, nanomedicine has already produced a healthy crop of significant products in which the nano dimension has made a significant contribution to product effectiveness. As the market grows towards maturity, it is timely to review the technology, see its practical applications so far, evaluate the participating companies, and look to the future of this marketplace.
 
This report is designed to satisfy the information needs of a wide variety of individuals involved in the pharmaceutical marketplace, including company senior management executives seeking to base their strategic decisions on the best available information on market forces and trends. However, it is also aimed at managers and executives in marketing, research, planning, and sales departments who need readable, comprehensive, and up-to-date background on the marketplace in which they are operating.

This report discusses the implications of technology and commercial trends in the context of the current size and growth of the pharmaceutical market, both in global terms and analyzed by the most important national markets. The important technologies supporting nanomedicine are reviewed, and the nature and structure of the nanomedicine industry is discussed with profiles of the leading 60-plus companies, including recent M&A activity. Five-year sales forecasts are provided for the national markets and the major therapeutic categories of products involved.
 
Market figures are based on revenues at the manufacturer level and are projected at 2009-dollar value without attempting to predict the effect of inflation or deflation.
Therapeutic categories quantified and forecast include cancer, CNS diseases, infections, and cardiovascular.   Country markets analyzed are the U.S., Japan, Germany, France, the UK, Italy, and Spain.

THIS REPORT:

  • Develops projections for the global nanomedicine market and for selected national markets, as well as the global markets by major nanotechologies and clinical applications. It will provide data for 2008 and estimates for 2009, and forecast the market and its compound annual growth rate (CAGR) from 2009 to 2014.
  • Discusses clinical applications to be developed, including cancer diagnosis and therapy, drug-delivery systems, biosensors, bone and dental repair, and coatings, such as those for stents.
  • Describes nanotechnologies such as fullerenes (buckyballs) as drug carriers, nanotubules for drug delivery, nanoparticles (e.g., liposomes, dendrimers, micelles), nanospheres, and molecular nanotechnology.
  • Explains that financing for start-up businesses is derived from various sources, including venture capital and government grants, and that there is also a considerable amount of activity in university research laboratories and scientific foundations.


TABLE OF CONTENTS

Chapter- 1: INTRODUCTION

STUDY GOALS AND OBJECTIVES

1

REASONS FOR DOING THE STUDY

1

INTENDED AUDIENCE

1

SCOPE OF REPORT

2

MARKET ANALYSES AND FORECASTS

2

METHODOLOGY

2

INFORMATION SOURCES

2

DISCLAIMER

3

 

Chapter-2: SUMMARY

RESEARCH AND COMMERCIALIZATION

4

APPLICATIONS

4

DRUG DELIVERY

4

DRUGS AND THERAPY

5

IN VIVO IMAGING

5

IN VITRO DIAGNOSTICS

5

BIOMATERIALS

5

ACTIVE IMPLANTS

5

MARKET

5

SUMMARY TABLE NANOMEDICAL GLOBAL SALES BY THERAPEUTIC AREA, THROUGH 2014 ($ BILLIONS)

6

SUMMARY FIGURE NANOMEDICAL GLOBAL SALES BY THERAPEUTIC AREA, 2006-2014 ($ BILLIONS)

6

 

Chapter-3: OVERVIEW

MEDICAL NANOTECHNOLOGY: NANOMEDICINE

7

FUTURE POSSIBILITIES

7

MARKET POTENTIAL

8

ABOUT NANOTECHNOLOGY

8

THE MANY USES OF NANOTECHNOLOGY

10

MEDICAL APPLICATIONS

10

ENVIRONMENTAL APPLICATIONS

10

MILITARY APPLICATIONS

11

COSMETICS

11

APPLICATIONS IN DEVELOPMENT

11

THE TOOLS OF NANOTECHNOLOGY

12

C60/FULLERENES

12

CARBON NANOTUBES

12

NANOPARTICLES

12

NANOWIRES

13

MOLECULAR NANOTECHNOLOGY

13

RISKS OF NANOTECHNOLOGY

13

POISON/TOXICITY

13

NANOTECHNOLOGY IN THE MARKETPLACE

14

 

Chapter-4: NANOMEDICINE

DEVELOPMENT OF NANOMEDICAL TECHNOLOGIES

17

TABLE 1 NANOMEDICINE TIMESCALE

17

TABLE 2 MAIN NANOTECHNOLOGIES USED IN MEDICINE, WITH APPLICATIONS

18

LIPOSOMES

18

TABLE 3 MARKETED LIPOSOME NANOPHARMACEUTICALS

19

DENDRIMERS

20

TABLE 4 DENDRIMER PRODUCTS IN ADVANCED DEVELOPMENT

20

NANOCRYSTALS

20

TABLE 5 NANOCRYSTAL PHARMACEUTICALS

21

MICELLES

21

TABLE 6 MARKETED AND DEVELOPMENTAL PRODUCTS IN MICELLE FORM

22

FULLERENES

22

POLYMERIC NANOPARTICLES

23

THERAPEUTIC USES OF NANOMEDICINE

24

CANCER DIAGNOSTICS AND THERAPY

24

Silica Nanospheres

24

Nanoscale Hydrogel Shells

24

Photodynamic Therapy and Gold

25

Dendrimer Conjugates

26

Ligand-targeted Emulsion Technologies

26

Linear Cyclodextrin-containing Polymers

27

Smart Lipid-based Nanocarriers

27

Thermotherapy Using Magnetic Nanoparticles

28

Targeted Cell Destruction

28

Nanoshells

29

DRUG DELIVERY

29

Acusphere

29

AlphaRx

30

Aphios

30

Biodelivery Sciences

30

Bioral

31

Capsulution NanoScience

31

HealthPlus International

32

IGI

32

Labopharm

32

MagnaMedics

33

Nanocopoeia

33

Nanocrystal

33

NanoMed

34

Nanopharm

34

Nanocyte

35

Nanotherapeutics

35

Nanotrope

36

pSivida

36

SoluBest

37

Spherics

37

Telemolecular

37

INFECTION CONTROL

38

Silver Nanoparticles Against Infection

38

Detecting Nanobacteria

39

Killing Viruses

40

DIAGNOSTIC TOOLS

40

BioCrystal/InVitrogen

40

BioForce

41

Biophage

41

CombiMatrix

41

Farfield Sensors

42

GE Healthcare BioSciences

42

Immunicon

43

MagnaMedics

43

Nanogen

44

NanoSphere

44

Qiagen

45

Sphere

45

TransGenex

46

Veredus

46

VARIOUS THERAPEUTIC TARGETS AND TECHNOLOGIES

47

Anthrax

47

Cholesterol

47

Artificial Retina

47

Nerve Regeneration

48

Crossing the Blood-Brain Barrier

48

Protecting Against Radiation Damage

49

Antibody Therapeutics

50

Hemostasis

50

Bone Fracture Repair

51

Dental Implant and Tissue Regeneration

51

Vaccine Adjuvant

51

Treatment of Thrombosis

52

Coatings for Stents and Other Devices

53

FUTURE TRENDS AND RESEARCH POSSIBILITIES

53

Noninvasive Nanodevices

54

Extracellular Devices

55

Intracellular Devices

55

Nanomachines to Control Tissue Healing

56

Eliminating Viruses

57

Correcting Chemistry

58

New Organs and Limbs

58

FUNDAMENTAL NANOTECHNOLOGY RESEARCH

58

U.S.

59

University at Albany-SUNY

59

Cornell University

59

University of Michigan

60

Rice University

60

University of Pennsylvania

61

University of Virginia

62

University of North Carolina

62

Ohio State University

63

Northwestern University

63

University of Pittsburgh

63

Case Western Reserve University

64

University of California at Berkeley

64

Europe

64

TABLE 7 EUROPEAN NANOCENTERS

65

Japan

65

Development of Active Targeting DDS

66

Development of Novel Tissue Engineering

66

Development of New Biomaterials

66

THE RISK FACTOR

67

MARKETS FOR NANOMEDICINE

68

TABLE 8 MARKETED NANOPHARMACEUTICALS

69

TABLE 9 MARKETED NANO-IMAGING, DIAGNOSTICS, BIOMATERIALS

70

MARKET DRIVERS

70

MARKET ESTIMATES AND FORECASTS

71

TABLE 10 NANOTECHNOLOGY REVENUES BY INDUSTRY SECTOR, 2010 (%)

71

Global Nanomedicine Market

72

TABLE 11 GLOBAL NANOMEDICINE MARKET, THROUGH 2014 ($ BILLIONS)

72

Main Product Categories

72

Drug Delivery

72

Molecular Diagnostics

73

Market Analysis by Clinical Application

74

Cancer

74

TABLE 12 MAJOR MARKETED ANTICANCER NANOPHARMACEUTICALS, 2008 ($ BILLIONS)

74

TABLE 13 MARKET FORECAST FOR CANCER NANOTHERAPEUTICS AND ANODIAGNOSTICS, THROUGH 2014 ($ BILLIONS)

75

CNS Disorders

75

TABLE 14 MAJOR MARKETED CNS NANOPHARMACEUTICALS, 2008 ($ MILLIONS)

75

TABLE 15 MARKET FORECAST FOR CNS NANOMEDICINES, THROUGH 2014 ($ BILLIONS)

76

Infection

76

TABLE 16 MAJOR MARKETED ANTI-INFECTIVE NANOPHARMACEUTICALS, 2008 ($ BILLIONS)

76

TABLE 17 MARKET FORECAST FOR ANTI-INFECTION NANOTHERAPEUTICS AND NANODIAGNOSTICS, THROUGH 2014 ($ BILLIONS)

77

Cardiovascular and Autoimmune Disorders

77

TABLE 18 MAJOR MARKETED NANOMEDICINES FOR CARDIOVASCULAR AND INFLAMMATORY DISEASES, 2008 ($ MILLIONS)

77

TABLE 19 MARKETS FOR CARDIOVASCULAR AND ANTI-INFLAMMATORY PRODUCTS, THROUGH 2014 ($ BILLIONS)

78

Regional and National Market Analysis

78

FIGURE 1 NATIONAL SHARES OF THE GLOBAL NANOMEDICINE MARKETPLACE, 2009 (%)

78

U.S.

79

TABLE 20 U.S. NANOMEDICINE MARKET: HISTORIC AND FORECAST DATA, THROUGH 2014 ($ BILLIONS/%)

79

Japan

80

TABLE 21 NANOMEDICINE MARKET IN JAPAN: HISTORIC AND FORECAST DATA, THROUGH 2014 ($ BILLIONS/%)

80

Europe

81

TABLE 22 NANOMEDICINE MARKET IN GERMANY: HISTORIC AND FORECAST DATA, THROUGH 2014 ($ BILLIONS/%)

81

TABLE 23 NANOMEDICINE MARKET IN FRANCE: HISTORIC AND FORECAST DATA, THROUGH 2014 ($ BILLIONS/%)

81

TABLE 24 NANOMEDICINE MARKET IN UNITED KINGDOM: HISTORIC AND FORECAST DATA, THROUGH 2014 ($ BILLIONS/%)

82

TABLE 25 NANOMEDICINE MARKET IN ITALY: HISTORIC AND FORECAST DATA, THROUGH 2014 ($ BILLIONS/%)

82

TABLE 26 NANOMEDICINE MARKET IN SPAIN: HISTORIC AND FORECAST DATA, THROUGH 2014 ($ BILLION/%)

82

 

Chapter-5: COMPANY PROFILES

ABLYNX NV

84

ABRAXIS BIOSCIENCE

85

ACRYMED INC.

87

ACUSPHERE INC.

88

ADVANCED MAGNETICS

90

ALLTRACEL

90

ALPHARX INC.

91

ANSON NANO-BIOTECHNOLOGY

93

APHIOS CORP.

93

PROTEIN NANOPARTICLES

94

POLYMER NANOSPHERES

94

PHOSPHOLIPID NANOSOMES

94

BIOCRYSTAL LTD

95

BIOFORCE NANOSCIENCES INC.

96

THE VIRICHIP VIRUS DETECTION PLATFORM

96

BIO-GATE AG

97

MEDICAL APPLICATIONS

98

BIOPHAGE PHARMA INC.

99

PRODUCTS

99

DEVELOPMENT THROUGH COLLABORATIONS:

99

PHAGES

100

BIOPHAN TECHNOLOGIES

101

BIOSANTÉ PHARMACEUTICALS INC.

102

NOVEL VACCINE ADJUVANT–BIOVANT

102

THERAPEUTIC DRUG DELIVERY PLATFORM—BIOAIR /BIOORAL

103

CALANDO PHARMACEUTICALS

104

C SIXTY

105

CAPSULUTION PHARMA AG

107

DRUG DELIVERY SYSTEMS

107

COMBIMATRIX

108

DRUG DEVELOPMENT

108

DAMAGE PREVENTION CONCEPT

110

ELAN DRUG TECHNOLOGIES

110

FARFIELD SCIENTIFIC

112

GE HEALTHCARE LIFE SCIENCES

114

HEALTHPLUS INTERNATIONAL INC.

115

IGI INC.

116

IMARX THERAPEUTICS INC.

117

SONOLYSIS

118

JR NANOTECH PLC

119

KEREOS, INC.

119

MRI AGENT FOR TUMOR DETECTION

120

TARGETED CHEMOTHERAPEUTICS FOR SOLID TUMORS

120

KI-0002 MRI AGENT FOR CARDIOVASCULAR DISEASE DETECTION

120

ANTI-RESTENOTIC

120

KEYSTONE NANO, INC.

121

NANOJACKETS

121

KLEINDIECK NANOTECHNIK

122

NANOWORKSTATION

122

LABOPHARM INC.

123

LIPLASOME PHARMA

125

LUMERA CORPORATION

127

NANOCAPTURE MICROARRAYS

128

MAGFORCE NANOTECHNOLOGIES AG

128

MAGNAMEDICS GMBH

130

MAGCUSTOM

130

Customized Nano- and Micro-Particles

130

EFFICIENT AND LOW-COST DIAGNOSTICS

131

MULTIFUNCTIONAL DRUG CARRIER

131

MICROFLUIDICS INTERNATIONAL CORPORATION

132

MIV THERAPEUTICS INC.

133

CARDIOVASCULAR HEART STENTS

134

MOLECULAR PROFILES

135

NANOBAC PHARMACEUTICALS INC

136

NANOBIO CORPORATION

137

NANOBIOTIX

140

NANOCARRIER CO. LTD.

142

NANOCOPOEIA

144

NANOCYTE INC

145

NANOGEN INC.

146

ELECTRONIC MICROARRAY

147

INSTRUMENTATION

147

Molecular Biology Workstation

147

Molecular Biology Workstation Cartridge

148

NanoChip 400 System

148

NANOINK INC.

149

NANOLOGIX INC.

150

NANOMED PHARMACEUTICALS, INC.

151

NANOMIX INC.

152

NANOPHARM AG

153

NANOSPECTRA BIOSCIENCES, INC.

154

NANOSPHERE INC.

155

NANOSTRUCTURES INC.

157

NANOSYN INC

158

NANOTHERAPEUTICS INC.

159

NANOTROPE INC.

161

NANOVIRICIDES INC.

162

FLUCIDE-I

162

NUCRYST PHARMACEUTICALS

163

NUTRALEASE

165

ORION INTEGRATED BIOSCIENCES INC.

166

GENOMIC SIGNATURES

166

RATIONAL ANTIVIRAL DEVELOPMENT

167

DISCOVERY OF MALARIA INVASION PATHWAYS

167

ORTHOVITA INC

168

PIONEER SURGICAL TECHNOLOGY

169

PSIVIDA LTD

169

QIAGEN N.V.

171

SOLUBEST LTD.

172

SPHERICS INC.

174

STARPHARMA HOLDINGS LTD

175

DENDRIMER NANOTECHNOLOGY

175

TECAN GROUP LTD.

176

TEMOLECULAR CORPORATION

177

TRANSGENEX NANOBIOTECH INC.

180

THERAPY

181

APPENDIX: GLOSSARY OF TERMS

182

TABLE 27 GLOSSARY OF TERMS

182

 

 

 

Warranty Information

Number of Pages: 184

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