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New PublicationsRESPIRATORY DRUGS MCP-1577
A GLOBAL STRATEGIC BUSINESS REPORT
CONTENTS
I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS
II. EXECUTIVE SUMMARY
1. Market Overview II-1
Respiratory Diseases - Common and Serious II-1
Rhinoviruses - Root Cause of Major Respiratory Diseases II-1
Leading Asthmatic Drugs and their Patent Expiries II-2
Antihistamine or Allergic Rhinitis Market II-2
Leading Anti-Allergy Drugs and Patent Expiry Years II-3
Current and Future Analysis II-3
Regional Perspective II-3
Product Segment Perspective II-3
2. Common Respiratory Diseases - Overview II-4
Influenza II-4
Asthma II-4
Factors Promoting Asthma II-5
Treatment II-5
Respiratory Distress Syndrome (RDS) II-5
Symptoms II-6
Complications Related to RDS II-6
Analysis of RDS II-6
Alternative Methods for the Treatment of RDS II-7
Preventive Measures II-7
Chronic Obstructive Pulmonary Disease II-8
Characteristics and Symptoms of COPD II-8
Risks Associated with COPD II-8
Bronchitis II-9
Respiratory Syncytial Virus (RSV) II-9
3. Treatment of Respiratory Diseases - An Overview II-10
Respiratory Therapy with Information Technology II-10
Antiviral Drugs for Controlling Influenza and RSV Infections II-10
Pulmonary Drug Delivery II-10
Why are Lungs Considered a Good Alternative? II-10
COPD - Taking a Toll on Human Lives II-11
Upper Respiratory Tract Infections (URIs) II-11
Respiratory Failure Management II-11
CPAP: Non-Invasive Respiration II-12
Face Masks: Carriers of Oxygen Therapy II-12
Endotracheal Intubation and Ventilatory Support II-12
Endotracheal Intubation Turns Perilous II-13
Ventilator Strategy II-13
Methods of Ventilation II-14
Weaning from the Ventilator II-15
Respiratory Support: A Broader Perspective II-15
Humidification II-15
Posture II-15
Physiotherapy II-15
Pharmacological Adjuncts II-15
Sedation II-16
New Drugs, Treatments Ease Life of Patients with Respiratory
Problems II-16
Progesterone II-16
Partial Liquid Ventilation II-17
Heliox II-17
High-level PREP II-18
Respiratory Failure II-18
Types of Respiratory Failure II-19
Factors Leading to Respiratory Failure II-19
Blockage of air passage II-19
Drug abuse or alcohol addiction II-19
Obesity II-19
Muscle weakness II-19
Lung disorders and diseases II-19
Abnormalities in Chest Walls II-19
Cellular Disorders II-19
Treatment for Respiratory Failure II-20
Role of Health Care Teams II-20
Long-Term Consequences of Respiratory Failures II-21
Preventive Measures II-21
Measures to Prevent the Recurrence of Respiratory Diseases II-21
Telithromycin: Treatment for Respiratory Disorders II-21
Consequences of Telithromycin II-22
4. Recent Industry Activity II-23
Arcadia Resources, Inc Acquires Remedy Therapeutics, L.L.C II-23
Sirna Forms Alliance with GlaxoSmithKline II-23
Pharmaxis Ltd and Nigaard Pharma Enters into Distribution
Agreement II-23
Teva Regains Leadership Position through Ivax Acquisition II-23
AstraZeneca Submits Symbicort for US FDA Approval II-24
Ranbaxy Laboratories Receives FDA Approval II-24
Innovata Inks Development Agreement for Duohaler II-24
Novartis Obtains License from Arrow Therapeutics for A60444
Molecule Inhibitor II-24
Arakis Ltd and Vectura Group plc Initiate Phase IIb Clinical
Trial of NVA237 II-25
Schering-Plough Receives FDA Approval for Asmanex II-25
Isis Pharmaceuticals Develops ISIS 369645 II-25
Inyx Acquires Celltech Manufacturing Services from UCB II-25
Ashton Pharmaceuticals Partners with Innovata and Merck II-25
King Pharmaceuticals Collaborates with Inyx II-26
Inyx Pharma Ltd. Bags a Contract from Generics II-26
Alnylam Pharmaceuticals Initiates Phase I Trials on ALN-RSV01 II-27
MAP and Elan Extend their Agreement for Developing Advanced
Version of Asthma Drug II-27
Accentia Enters into Licensing Agreement with Collegium II-27
Novartis Inks Agreement with Arakis and Vectura II-28
Pfizer and Rigel Sign Collaborative Agreement II-28
NicOx Enters into Developing and Licensing Agreement with
Topigen II-29
Merck to Strike a Licensing Deal with Innovata for Developing
Respiratory Medicines II-29
Lannett Receives Approval from FDA for the Distribution of
Terbutaline Sulfate Tablets II-30
GlaxoSmithKline Licenses Inhaled Respiratory Therapy from
Theravance II-30
Novartis' Sandoz Completes Acquisition of Hexal AG II-31
Sandoz Acquires Eon Labs II-31
SkyePharma, PLC Enters into License Agreement with
GlaxoSmithKline II-31
Kos Pharmaceuticals Signs Agreement with Aventis Pharmaceuticals II-31
US FDA Approves New Antibiotic, Ketek II-31
Zambon Terminates Single-Agent Inhaler Project II-32
Boehringer Ingelheim Pharmaceuticals Obtains FDA Approval for
Atrovent HFA II-32
Ranbaxy Receives FDA Approval for Loratadine and
Pseudoephedrine Sulfate Tablets II-32
Lincoln Pharmaceuticals Limited Introduces Gatilink, an
Antibiotic II-32
GlaxoSmithKline Forms Alliance with Theravance II-33
Etiologics Acquires Bayer's Pre-clinical Respiratory Research
Group II-33
IVAX Pharmaceutical Signs Pan-European Agreement with 3M II-33
GlaxoSmithKline Inks Agreement with Theravance II-33
Cadila Pharmaceuticals Ltd Launches Montelast for Asthma II-33
Alpharma Unveils Generic Loratadine Syrup II-33
Dr. Reddy's Laboratories Launches Brancho-Vaxom II-33
5. Focus on Select Players II-34
Accentia Biopharmaceuticals, Inc. (US) II-34
Aerogen, Inc. (US) II-34
Aerovance, Inc (US) II-34
airPharma (US) II-34
AstraZeneca (UK) II-35
Aventis Pharma Limited (India) II-35
Bespak (UK) II-35
Boehringer Ingelheim Pharmaceuticals, Inc (Germany) II-35
Cadila Pharmaceuticals (India) II-35
Dr. Reddy's Laboratories (India) II-36
EvoGenix (Australia) II-36
GlaxoSmithKline (US) II-37
GlaxoSmithKline Pharmaceuticals Ltd. (India) II-37
Inyx, Inc. (US) II-37
The Merck Generics Group (Germany) II-37
Novartis AG (Switzerland) II-38
Pfizer, Inc. (US) II-38
Ranbaxy Laboratories Limited (India) II-39
Respironics, Inc (US) II-40
Sandoz International GmbH (Germany) II-40
Schering-Plough Corp (US) II-41
6. Global Market Perspective II-42
Table 1: Recent Past, Current and Future Analysis for
Respiratory Drugs by Geographic Region - US, Canada, Japan,
Europe and Rest of World Markets Independently Analyzed by
Annual Sales in US$ Million for the Years 2000 through 2010
(includes corresponding Graph/Chart) II-42
Table 2: World 10-Year Perspective for Respiratory Drugs by
Geographic Region - Percentage Breakdown of Dollar Sales for
US, Canada, Japan, Europe and Rest of World Markets for the
Years 2000, 2006 and 2010 (includes corresponding Graph/Chart) II-42
Table 3: World Recent Past, Current and Future Analysis for
Asthma Drugs by Geographic Region - US, Canada, Japan, Europe
and Rest of World Markets Independently Analyzed by Annual
Sales in US$ Million for the Years 2000 through 2010
(includes corresponding Graph/Chart) II-43
Table 4: World 10-Year Perspective for Asthma Drugs by
Geographic Region - Percentage Breakdown of Dollar Sales for
US, Canada, Japan, Europe and Rest of World Markets for the
Years 2000, 2006 and 2010 (includes corresponding Graph/Chart) II-43
Table 5: World Recent Past, Current and Future Analysis for
Allergic Rhinitis Drugs by Geographic Region - US, Canada,
Japan, Europe and Rest of World Markets Independently Analyzed
by Annual Sales in US$ Million for the Years 2000 through
2010 (includes corresponding Graph/Chart) II-44
Table 6: World 10-Year Perspective for Allergic Rhinitis
Drugs by Geographic Region - Percentage Breakdown of Dollar
Sales for US, Canada, Japan, Europe and Rest of World Markets
for the Years 2000, 2006 and 2010 (includes corresponding
Graph/Chart) II-44
Table 7: World Recent Past, Current and Future Analysis for
Chronic Obstructive Pulmonary Disease (COPD) Drugs by
Geographic Region - US, Canada, Japan, Europe and Rest of
World Markets Independently Analyzed by Annual Sales in US$
Million for the Years 2000 through 2010 (includes
corresponding Graph/Chart) II-45
Table 8: World 10-Year Perspective for Chronic Obstructive
Pulmonary Disease (COPD) Drugs by Geographic Region -
Percentage Breakdown of Dollar Sales for US, Canada, Japan,
Europe and Rest of World Markets for the Years 2000, 2006 and
2010 (includes corresponding Graph/Chart) II-45
III. MARKET
1. The United States III-1
A.Market Analysis III-1
Current & Future Analysis III-1
Market Scenario III-1
Asthma III-1
COPD III-2
Leading Respiratory Drug Brands III-2
Strategic Corporate Developments III-2
Focus on Select Players III-8
B.Market Analytics III-11
Table 9: US Recent Past, Current and Future Analysis for
Respiratory Drugs by Product Segment - Asthma Drugs,
Allergic Rhinitis Drugs and Chronic Obstructive Pulmonary
Disease (COPD) Drugs Independently Analyzed by Annual Sales
in US$ Million for the Years 2000 through 2010 (includes
corresponding Graph/Chart) III-11
Table 10: US 10-Year Perspective for Respiratory Drugs by
Product Segment - Percentage Breakdown of Dollar Sales for
Asthma Drugs, Allergic Rhinitis Drugs and Chronic
Obstructive Pulmonary Disease (COPD) Drugs for the Years
2000, 2006 and 2010 (includes corresponding Graph/Chart) III-11
2. Canada III-12
Market Analysis III-12
Table 11: Canadian Recent Past, Current and Future Analysis
for Respiratory Drugs by Product Segment - Asthma Drugs,
Allergic Rhinitis Drugs and Chronic Obstructive Pulmonary
Disease (COPD) Drugs Independently Analyzed by Annual Sales
in US$ Million for the Years 2000 through 2010 (includes
corresponding Graph/Chart) III-12
Table 12: Canadian 10-Year Perspective for Respiratory Drugs
by Product Segment - Percentage Breakdown of Dollar Sales
for Asthma Drugs, Allergic Rhinitis Drugs and Chronic
Obstructive Pulmonary Disease (COPD) Drugs for the Years
2000, 2006 and 2010 (includes corresponding Graph/Chart) III-13
3. Japan III-14
Market Analysis III-14
Table 13: Japanese Recent Past, Current and Future Analysis
for Respiratory Drugs by Product Segment - Asthma Drugs,
Allergic Rhinitis Drugs and Chronic Obstructive Pulmonary
Disease (COPD) Drugs Independently Analyzed by Annual Sales
in US$ Million for the Years 2000 through 2010 (includes
corresponding Graph/Chart) III-14
Table 14: Japanese 10-Year Perspective for Respiratory Drugs
by Product Segment - Percentage Breakdown of Dollar Sales
for Asthma Drugs, Allergic Rhinitis Drugs and Chronic
Obstructive Pulmonary Disease (COPD) Drugs for the Years
2000, 2006 and 2010 (includes corresponding Graph/Chart) III-15
4. Europe III-16
A.Market Analysis III-16
Current & Future Analysis III-16
Strategic Corporate Developments III-16
Focus on Select Players III-20
B.Market Analytics III-23
Table 15: European Recent Past, Current and Future Analysis
for Respiratory Drugs by Product Segment - Asthma Drugs,
Allergic Rhinitis Drugs and Chronic Obstructive Pulmonary
Disease (COPD) Drugs Independently Analyzed by Annual Sales
in US$ Million for the Years 2000 through 2010 (includes
corresponding Graph/Chart) III-23
Table 16: European 10-Year Perspective for Respiratory Drugs
by Product Segment - Percentage Breakdown of Dollar Sales
for Asthma Drugs, Allergic Rhinitis Drugs and Chronic
Obstructive Pulmonary Disease (COPD) Drugs for the Years
2000, 2006 and 2010 (includes corresponding Graph/Chart) III-23
5. Rest of World III-24
A.Market Analysis III-24
Current & Future Analysis III-24
Strategic Corporate Developments III-24
Focus on Select Players III-25
B.Market Analytics III-29
Table 17: Rest of World Recent Past, Current and Future
Analysis for Respiratory Drugs by Product Segment - Asthma
Drugs, Allergic Rhinitis Drugs and Chronic Obstructive
Pulmonary Disease (COPD) Drugs Independently Analyzed by
Annual Sales in US$ Million for the Years 2000 through 2010
(includes corresponding Graph/Chart) III-29
Table 18: Rest of World 10-Year Perspective for Respiratory
Drugs by Product Segment - Percentage Breakdown of Dollar
Sales for Asthma Drugs, Allergic Rhinitis Drugs and Chronic
Obstructive Pulmonary Disease (COPD) Drugs for the Years
2000, 2006 and 2010 (includes corresponding Graph/Chart) III-29
IV. COMPETITIVE LANDSCAPE
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